PRE-CLINICAL EVALUATION OF CD38 CHIMERIC ANTIGEN RECEPTOR ENGINEERED T CELLS FOR THE TREATMENT OF MULTIPLE MYELOMA

Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma

Adoptive transfer of chimeric antigen receptor-transduced T cells is a promising strategy for cancer immunotherapy.The CD38 molecule, with its high expression on multiple myeloma cells, appears a suitable target for depileve easy clean antibody therapy.Prompted by this, we used three different CD38 antibody sequences to generate second-generation r

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Ichthyosporea: a window into the origin of animals

Abstract Ichthyosporea is read more an underexplored group of unicellular eukaryotes closely related to animals.Thanks to their phylogenetic position, genomic content, and development through a multinucleate coenocyte reminiscent of some animal embryos, the members of Ichthyosporea are being increasingly recognized as pivotal to the study of animal

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Study on the Structural Design and Obstacle Barrier Performance of Double Pendulum Arms Crawler Deformable Robot

In order to make the best obstacle performance of the crawler deformable robot, and to ensure that the crawler length does not change and continue to tension during the change process, the ellipse theorem and the elliptical rule principle are applied to the robot configuration design, and a read more new type of crawler deformable robot is develope

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